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About University of Galway
About University of Galway
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Guiding Breakthrough Research at University of Galway
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Community Engagement
Community Engagement
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Mathematical and Statistical Sciences
Dr Emma Holian
BSc, PhD
Biography
Research Interests
Research Projects
| Project | Start Date | End Date | |
|---|---|---|---|
| CLUSTER ANALYSIS MXT GLMM E HOLIAN | 01-APR-09 | 28-MAY-12 |
Peer Reviewed Journals
| Year | Publication | |
|---|---|---|
| (2021) | 'Survival outcomes are associated with genomic instability in luminal breast cancers'
King, L; Flaus, A; Holian, E; Golden, A (2021) 'Survival outcomes are associated with genomic instability in luminal breast cancers'. Plos One, [Details] |
|
| (2020) | 'Assessment of groundwater processes using censored data analysis incorporating non-detect chemical, physical, and biological data'
McGrory, E;Holian, E;Morrison, L (2020) 'Assessment of groundwater processes using censored data analysis incorporating non-detect chemical, physical, and biological data'. Journal Of Contaminant Hydrology, 235 [DOI] [Details] |
|
| (2020) | 'Relative and Absolute Expression Analysis of MicroRNAs Associated with Luminal A Breast Cancer- A Comparison'
Arabkari, V,Clancy, E,Dwyer, RM,Kerin, MJ,Kalinina, O,Holian, E,Newell, J,Smith, TJ (2020) 'Relative and Absolute Expression Analysis of MicroRNAs Associated with Luminal A Breast Cancer- A Comparison'. Pathology oncology research : POR, 26 :833-844 [DOI] [Details] |
|
| (2020) | 'Prospective Assessment of Systemic MicroRNAs as Markers of Response to Neoadjuvant Chemotherapy in Breast Cancer'
McGuire A;Casey MC;Waldron RM;Heneghan H;Kalinina O;Holian E;McDermott A;Lowery AJ;Newell J;Dwyer RM;Miller N;Keane M;Brown JAL;Kerin MJ; (2020) 'Prospective Assessment of Systemic MicroRNAs as Markers of Response to Neoadjuvant Chemotherapy in Breast Cancer'. Cancers, 12 (7) [DOI] [Details] |
|
| (2020) | 'Investigating the Potential and Pitfalls of EV-Encapsulated MicroRNAs as Circulating Biomarkers of Breast Cancer'
Moloney BM;Gilligan KE;Joyce DP;O'Neill CP;O'Brien KP;Khan S;Glynn CL;Waldron RM;Maguire CM;Holian E;Naughton E;Elhadi M;Grealish AB;Malone C;McDermott E;Dockery P;Ritter T;Prina-Mello A;Kerin MJ;Dwyer RM; (2020) 'Investigating the Potential and Pitfalls of EV-Encapsulated MicroRNAs as Circulating Biomarkers of Breast Cancer'. Cells, 9 (1) [DOI] [Details] |
|
| (2019) | 'Relative and Absolute Expression Analysis of MicroRNAs Associated with Luminal A Breast Cancer- A Comparison'
Arabkari V;Clancy E;Dwyer RM;Kerin MJ;Kalinina O;Holian E;Newell J;Smith TJ; (2019) 'Relative and Absolute Expression Analysis of MicroRNAs Associated with Luminal A Breast Cancer- A Comparison'. Pathology oncology research : POR, [DOI] [Details] |
|
| (2019) | 'Quantifying Argonaute 2 (Ago2) expression to stratify breast cancer'
Casey, MC;Prakash, A;Holian, E;McGuire, A;Kalinina, O;Shalaby, A;Curran, C;Webber, M;Callagy, G;Bourke, E;Kerin, MJ;Brown, JA (2019) 'Quantifying Argonaute 2 (Ago2) expression to stratify breast cancer'. BMC Cancer, 19 [DOI] [Details] |
|
| (2018) | 'Arsenic in Groundwater in South West Ireland: Occurrence, Controls, and Hydrochemistry'
McGrory, E,Holian, E,Alvarez-Iglesias, A,Bargary, N,McGillicuddy, EJ,Henry, T,Daly, E,Morrison, L (2018) 'Arsenic in Groundwater in South West Ireland: Occurrence, Controls, and Hydrochemistry'. Frontiers in Environmental Science, 6 [DOI] [ARAN Link] [Details] |
|
| (2019) | 'Quantifying Tip60 (Kat5) stratifies breast cancer'
McGuire, A,Casey, MC,Shalaby, A,Kalinina, O,Curran, C,Webber, M,Callagy, G,Holian, E,Bourke, E,Kerin, MJ,Brown, JAL (2019) 'Quantifying Tip60 (Kat5) stratifies breast cancer'. Scientific Reports, 9 [DOI] [Details] |
|
| (2017) | 'Differential impact of hormone receptor status on survival and recurrence for HER2 receptor-positive breast cancers treated with Trastuzumab'
McGuire, A,Kalinina, O,Holian, E,Curran, C,Malone, CA,McLaughlin, R,Lowery, A,Brown, JAL,Kerin, MJ (2017) 'Differential impact of hormone receptor status on survival and recurrence for HER2 receptor-positive breast cancers treated with Trastuzumab'. Breast Cancer Research And Treatment, 164 :221-229 [DOI] [Details] |
|
| (2016) | 'Screening of exosomal microRNAs from colorectal cancer cells'
Clancy, C,Khan, S,Glynn, CL,Holian, E,Dockery, P,Lalor, P,Brown, JAL,Joyce, MR,Kerin, MJ,Dwyer, RM (2016) 'Screening of exosomal microRNAs from colorectal cancer cells'. Cancer Biomarkers, 17 :427-435 [DOI] [ARAN Link] [Details] |
|
| (2014) | 'An Alternative Estimation Approach for the Heterogeneity Linear Mixed Model'
Martinez, MJ,Holian, E (2014) 'An Alternative Estimation Approach for the Heterogeneity Linear Mixed Model'. Communications In Statistics-Simulation And Computation, 43 :2628-2638 [DOI] [Details] |
|
| (2014) | 'Clustering longitudinal profiles using P-splines and mixed effects models applied to time-course gene expression data'
Coffey, N,Hinde, J,Holian, E (2014) 'Clustering longitudinal profiles using P-splines and mixed effects models applied to time-course gene expression data'. Computational Statistics & Data Analysis, 71 :14-29 [DOI] [Details] |
Conference Publications
| Year | Publication | |
|---|---|---|
| (2007) | 15th European Young Statisticians Meeting, EYSM 2007, Spain
Holian E. (2007) Mixture-Regression Cluster Model applied to Longitudinal Microarray Experiments 15th European Young Statisticians Meeting, EYSM 2007, Spain Spain, , 10-SEP-07 - 14-SEP-07 , pp.62-62 [Details] |
|
| (2004) | 19th International Workshop on Statistical Modelling
Holian, E and Hinde, J.P (2004) Microarray experiments for gene expression studies in fish stress studies 19th International Workshop on Statistical Modelling [Details] |
Abstract
| Year | Publication | |
|---|---|---|
| (2015) | Exosome-mediated trafficking of microRNAs by breast cancer cells.
Joyce, DP,Glynn, CL,Brown, J,Holian, E,Dockery, P,Kerin, MJ,Dwyer, RM (2015) Exosome-mediated trafficking of microRNAs by breast cancer cells. Abstract [Details] |
|
| (2015) | Investigation of exosome-encapsulated microRNAs as potential circulating biomarkers of breast cancer.
Joyce, DP,Higgins, M,Glynn, CL,Brown, J,Holian, E,Dockery, P,Kerin, MJ,Dwyer, RM (2015) Investigation of exosome-encapsulated microRNAs as potential circulating biomarkers of breast cancer. Abstract [Details] |
|
| (2015) | Exosome-mediated trafficking of microRNAs by basal breast cancer cells in vitro.
Joyce, DP,Glynn, CL,Higgins, M,Brown, J,Holian, E,Dockery, P,Kerin, MJ,Dwyer, RM (2015) Exosome-mediated trafficking of microRNAs by basal breast cancer cells in vitro. Abstract [Details] |
|
| (2014) | Exosome-Encapsulated MicroRNAs Secreted by Colorectal Cancer Cells: Mediators of Intercellular Cross-Talk in the Tumour Micro-Environment.
Clancy, C,Brown, J,Holian, E,Joyce, M,Kerin, MJ,Dwyer, RM (2014) Exosome-Encapsulated MicroRNAs Secreted by Colorectal Cancer Cells: Mediators of Intercellular Cross-Talk in the Tumour Micro-Environment. Abstract [Details] |
|
| (2014) | Secretion of Exosome-Encapsulated MicroRNAs by Basal Breast Cancer Cells in Vitro.
Joyce, D,Glynn, C,Brown, J,Holian, E,Dockery, P,Kerin, MJ,Dwyer, R (2014) Secretion of Exosome-Encapsulated MicroRNAs by Basal Breast Cancer Cells in Vitro. Abstract [Details] |
Honours and Awards
| Year | Title | Awarding Body | |
|---|---|---|---|
| 2015 | Nomination for NUIG CELT teaching award | - | |
| 2011 | Nomination for NUIG CELT teaching award | - | |
| 2007 | Recipient of one of two nominations awarded by the Irish Statistical Association (ISA) to represent Ireland at the European Young Statisticians Meeting EYSM 2007 Spain | - | |
| 2005 | Finalist - Embark Initiative Physical Sciences Communication awards | Embark Initiative | |
| 2002 | IRCSET scholarship | IRCSET |
Professional Associations
| Association | Function | From / To | |
|---|---|---|---|
| Irish Statistical Association ISA | Executive Committee member | 14-MAY-08 / 11-MAY-11 | |
| Irish Statistical Association, ISA | Ordinary member | 12-MAY-03 / |
Committees
| Committee | Function | From / To | |
|---|---|---|---|
| School of Mathematics, Statistics and Applied Mathematics, Learning & Teaching Committee | Chair | / | |
| Programme Board B.Sc. Mathematical Science | Chair Programme Director | 01-MAY-09 / |
Teaching Interests
Current Postgraduate Students (Research)
| Student | Degree Type | Type | |
|---|---|---|---|
| Maxwell Paganga | Doctorate - Structured PhD (Science) | Supervisor | |
| Olga Kalinina | Doctorate - Structured PhD (Science) | Supervisor | |
| Lydia King | Doctorate - Structured PhD (Science) | Supervisor |
Modules Taught
| Term/Year | Module Title | Module Code | Subject / Desc | |
|---|---|---|---|---|
| Semester 1 2018-2020 | Probability Models | ST1111 | ||
| Year-long/2018-2019 | Statistics | ST2352 | ||
| Semester 2 2015-2016 | Statistics | ST113 | ||
| Semester 2 2016 | Advanced Statistical Methods for Business | ST2218 | ||
| Semester 2 2016 | Introduction to Statistical Methods | ST1109 | ||
| Semester 1 2006 | Statistics I | ST237(MA237) | ||
| Semester 1 2008 | Applied Statistics | MA322 | ||
| Semester 1 2010 | Probability | ST112(MA112) | ||
| Semester 1 2012-2015 | Statistical Methods for Business | MA109 | ||
| Semester 1 2013 -2019 | Applied Statistics 1 | ST311 | ||
| Semester 2 2008-2019 | Statistical Methods for Business | ST2217 | ||
| Semester 2 2009-2011 | Mathematics & Statistics for Business | MA114 | ||
| Semester 2, 2009-2020 | Advanced Statistical Methods in Business | ST2218 | ||
| Year long, 2008-2014, running every 2nd year | Statistics via blended learning/distance learning | MA351.3 |
Internal Collaborators
| Name | Description of Collaboration | |
|---|---|---|
| Internal Collaborators |
External Collaborators
| Name | Organisation / Institute | Country | Description of Collaboration | |
|---|---|---|---|---|
| External Collaborators |
