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Medicine

Dr Aideen O'Doherty

B.Sc., Ph.D

 
researcher
 

Biography

Peer Reviewed Journals

  Year Publication
(2007) 'OxLDL-induced gene expression patterns in CASMC are mimicked in apoE-/-mice aortas'
Reeve, J, Stenson-Cox, C, O'Doherty, A, Porn-Ares, I, Ares, M, O'Brien, T, Samali, A (2007) 'OxLDL-induced gene expression patterns in CASMC are mimicked in apoE-/-mice aortas'. Biochemical and Biophysical Research Communications, 356 (3):681-686 [DOI] [Details]
(2007) 'OxLDL-induced gene expression patterns in CASMC are mimicked in apoE(-/-) mice aortas'
Reeve, JLV,Stenson-Cox, C,O'Doherty, A,Porn-Ares, I,Ares, M,O'Brien, T,Samali, A (2007) 'OxLDL-induced gene expression patterns in CASMC are mimicked in apoE(-/-) mice aortas'. Biochemical And Biophysical Research Communications, 356 :681-686 [DOI] [Details]
(2007) 'OxLDL-induced gene expression patterns in CASMC are mimicked in apoE-/- mice aortas'
Reeve JL, Stenson-Cox C, O'Doherty A, Pörn-Ares I, Ares M, O'Brien T, Samali A (2007) 'OxLDL-induced gene expression patterns in CASMC are mimicked in apoE-/- mice aortas'. Biochem, 356 (3):681-686 [DOI] [Details]
(2008) 'Gene delivery to the vasculature mediated by low-titre adeno-associated virus serotypes 1 and 5'
Sen, S,Conroy, S,Hynes, SO,McMahon, J,O'Doherty, A,Bartlett, JS,Akhtar, Y,Adegbola, T,Connolly, CE,Sultan, S,Barry, F,Katusic, ZS,O'Brien, T (2008) 'Gene delivery to the vasculature mediated by low-titre adeno-associated virus serotypes 1 and 5'. Journal Of Gene Medicine, 10 :143-151 [DOI] [Details]
(2008) 'Gene delivery to the vasculature mediated by low-titre adeno-associated virus serotypes 1 and 5'
Sen, S.,Conroy, S.,Hynes, S. O.,McMahon, J.,O'Doherty, A.,Bartlett, J. S.,Akhtar, Y.,Adegbola, T.,Connolly, C. E.,Sultan, S.,Barry, F.,Katusic, Z. S.,O'Brien, T. (2008) 'Gene delivery to the vasculature mediated by low-titre adeno-associated virus serotypes 1 and 5'. J Gene Med, 10 (22):143-51 [Details]
(2008) 'Gene delivery to the vasculature mediated by low-titre adeno-associated virus serotypes 1 and 5'
Sen, S;Conroy, S;Hynes, SO;McMahon, J;O'Doherty, A;Bartlett, JS;Akhtar, Y;Adegbola, T;Connolly, CE;Sultan, S;Barry, F;Katusic, ZS;O'Brien, T (2008) 'Gene delivery to the vasculature mediated by low-titre adeno-associated virus serotypes 1 and 5'. Journal Of Gene Medicine, 10 :143-151 [DOI] [Details]
(2009) 'Comparison of Viral and Nonviral Vectors for Gene Transfer to Human Endothelial Progenitor Cells'
Kealy, B,Liew, A,McMahon, JM,Ritter, T,O'Doherty, A,Hoare, M,Greiser, U,Vaughan, EE,Maenz, M,O'Shea, C,Barry, F,O'Brien, T (2009) 'Comparison of Viral and Nonviral Vectors for Gene Transfer to Human Endothelial Progenitor Cells'. Tissue Engineering Part C-Methods, 15 :223-231 [DOI] [Details]
(2009) 'Comparison of viral and nonviral vectors for gene transfer to human endothelial progenitor cells'
Kealy, B.,Liew, A.,McMahon, J. M.,Ritter, T.,O'Doherty, A.,Hoare, M.,Greiser, U.,Vaughan, E. E.,Maenz, M.,O'Shea, C.,Barry, F.,O'Brien, T. (2009) 'Comparison of viral and nonviral vectors for gene transfer to human endothelial progenitor cells'. Tissue Eng Part C Methods, 15 (22):223-31 [Details]
(2009) 'Comparison of Viral and Nonviral Vectors for Gene Transfer to Human Endothelial Progenitor Cells'
Kealy, B;Liew, A;McMahon, JM;Ritter, T;O'Doherty, A;Hoare, M;Greiser, U;Vaughan, EE;Maenz, M;O'Shea, C;Barry, F;O'Brien, T (2009) 'Comparison of Viral and Nonviral Vectors for Gene Transfer to Human Endothelial Progenitor Cells'. Tissue Engineering Part C-Methods, 15 :223-231 [DOI] [Details]
(2011) 'Development and characterisation of a novel rat model of Parkinson's disease induced by sequential intranigral administration of AAV-α-synuclein and the pesticide, rotenone'
Mulcahy P, O'Doherty A, Paucard A, O'Brien T, Kirik D, Dowd E. (2011) 'Development and characterisation of a novel rat model of Parkinson's disease induced by sequential intranigral administration of AAV-α-synuclein and the pesticide, rotenone'. Journal Of Neuroscience, [Details]
(2012) 'Development and characterisation of a novel rat model of Parkinson’s disease induced by sequential intra-nigral administration of AAV-a-synuclein and the pesticide, rotenone'
Mulcahy P, O’Doherty A, Paucard A, O’Brien T, Kirik D & Dowd E (2012) 'Development and characterisation of a novel rat model of Parkinson’s disease induced by sequential intra-nigral administration of AAV-a-synuclein and the pesticide, rotenone'. Neuroscience, [Details]
(2012) 'DEVELOPMENT AND CHARACTERISATION OF A NOVEL RAT MODEL OF PARKINSON'S DISEASE INDUCED BY SEQUENTIAL INTRANIGRAL ADMINISTRATION OF AAV-alpha-SYNUCLEIN AND THE PESTICIDE, ROTENONE'
Mulcahy, P,O'Doherty, A,Paucard, A,O'Brien, T,Kirik, D,Dowd, E (2012) 'DEVELOPMENT AND CHARACTERISATION OF A NOVEL RAT MODEL OF PARKINSON'S DISEASE INDUCED BY SEQUENTIAL INTRANIGRAL ADMINISTRATION OF AAV-alpha-SYNUCLEIN AND THE PESTICIDE, ROTENONE'. Neuroscience, 203 :170-179 [DOI] [Details]
(2012) 'DEVELOPMENT AND CHARACTERISATION OF A NOVEL RAT MODEL OF PARKINSON'S DISEASE INDUCED BY SEQUENTIAL INTRANIGRAL ADMINISTRATION OF AAV-alpha-SYNUCLEIN AND THE PESTICIDE, ROTENONE'
Mulcahy, P;O'Doherty, A;Paucard, A;O'Brien, T;Kirik, D;Dowd, E (2012) 'DEVELOPMENT AND CHARACTERISATION OF A NOVEL RAT MODEL OF PARKINSON'S DISEASE INDUCED BY SEQUENTIAL INTRANIGRAL ADMINISTRATION OF AAV-alpha-SYNUCLEIN AND THE PESTICIDE, ROTENONE'. Neuroscience, 203 :170-179 [DOI] [Details]
(2013) 'The behavioural and neuropathological impact of intranigral AAV-alpha-synuclein is exacerbated by systemic infusion of the Parkinson's disease-associated pesticide, rotenone, in rats'
Mulcahy, P,O'Doherty, A,Paucard, A,O'Brien, T,Kirik, D,Dowd, E (2013) 'The behavioural and neuropathological impact of intranigral AAV-alpha-synuclein is exacerbated by systemic infusion of the Parkinson's disease-associated pesticide, rotenone, in rats'. Behavioural Brain Research, 243 :6-15 [DOI] [Details]
(2013) 'The behavioural and neuropathological impact of intranigral AAV-alpha-synuclein is exacerbated by systemic infusion of the Parkinson's disease-associated pesticide, rotenone, in rats'
Mulcahy, P;O'Doherty, A;Paucard, A;O'Brien, T;Kirik, D;Dowd, E (2013) 'The behavioural and neuropathological impact of intranigral AAV-alpha-synuclein is exacerbated by systemic infusion of the Parkinson's disease-associated pesticide, rotenone, in rats'. Behavioural Brain Research, 243 :6-15 [DOI] [Details]
(2014) 'Heat Shock Protein 70 Reduces alpha-Synuclein-Induced Predegenerative Neuronal Dystrophy in the alpha-Synuclein Viral Gene Transfer Rat Model of Parkinson's Disease'
Moloney, TC,Hyland, R,O'Toole, D,Paucard, A,Kirik, D,O'Doherty, A,Gorman, AM,Dowd, E (2014) 'Heat Shock Protein 70 Reduces alpha-Synuclein-Induced Predegenerative Neuronal Dystrophy in the alpha-Synuclein Viral Gene Transfer Rat Model of Parkinson's Disease'. Cns Neuroscience & Therapeutics, 20 :50-58 [DOI] [Details]
(2014) 'Heat Shock Protein 70 Reduces alpha-Synuclein-Induced Predegenerative Neuronal Dystrophy in the alpha-Synuclein Viral Gene Transfer Rat Model of Parkinson's Disease'
Moloney, TC;Hyland, R;O'Toole, D;Paucard, A;Kirik, D;O'Doherty, A;Gorman, AM;Dowd, E (2014) 'Heat Shock Protein 70 Reduces alpha-Synuclein-Induced Predegenerative Neuronal Dystrophy in the alpha-Synuclein Viral Gene Transfer Rat Model of Parkinson's Disease'. Cns Neuroscience & Therapeutics, 20 :50-58 [DOI] [Details]
(2016) 'Differentiation of Vascular Stem Cells Contributes to Ectopic Calcification of Atherosclerotic Plaque'
Leszczynska A;O'Doherty A;Farrell E;Pindjakova J;O'Brien FJ;O'Brien T;Barry F;Murphy M; (2016) 'Differentiation of Vascular Stem Cells Contributes to Ectopic Calcification of Atherosclerotic Plaque'. Stem Cells (Dayton, Ohio), 34 (4) [DOI] [ARAN Link] [Details]
(2016) 'Differentiation of Vascular Stem Cells Contributes to Ectopic Calcification of Atherosclerotic Plaque'
Leszczynska, A,O'Doherty, A,Farrell, E,Pindjakova, J,O'Brien, FJ,O'Brien, T,Barry, F,Murphy, M (2016) 'Differentiation of Vascular Stem Cells Contributes to Ectopic Calcification of Atherosclerotic Plaque'. Stem Cells, 34 :913-923 [DOI] [Details]
(2016) 'Differentiation of Vascular Stem Cells Contributes to Ectopic Calcification of Atherosclerotic Plaque'
Leszczynska, A;O'Doherty, A;Farrell, E;Pindjakova, J;O'Brien, FJ;O'Brien, T;Barry, F;Murphy, M (2016) 'Differentiation of Vascular Stem Cells Contributes to Ectopic Calcification of Atherosclerotic Plaque'. Stem Cells (Dayton, Ohio), 34 :913-923 [DOI] [Details]

Conference Publications

  Year Publication
(2011) Heart 97(20):e7
Leszczynska, A,O'Doherty, A,Barry, F,O'Brien, T,Murphy, M (2011) 8 Ossification of atherosclerotic plaque: the role of vessel derived stem cells Heart 97(20):e7 [Details]
(2013) Irish Journal of Medical Science
Moloney, T., R. Hyland, D. O'Toole, A. Paucard, D. Kirik, A.O. Doherty, A. Gorman, and Dowd, E. (2013) HSP70 reduces alpha-synuclein-induced neuronal pathology in the alpha-synuclein viral gene transfer rat model of Parkinson's disease Irish Journal of Medical Science , pp.182: S121-S122 [Details]

Conference Contributions

  Year Publication
(2011) OSSIFICATION OF ATHEROSCLEROTIC PLAQUE: THE ROLE OF VESSEL DERIVED STEM CELLS,
Leszczynska, A,O'Doherty, A,Barry, F,O'Brien, T,Murphy, M (2011) HEART. OSSIFICATION OF ATHEROSCLEROTIC PLAQUE: THE ROLE OF VESSEL DERIVED STEM CELLS, dfg , 14-FEB-12 - 16-FEB-12. [Details]

Abstract

  Year Publication
(1995) RAPID LATEX ASSAY OF MYOGLOBIN FOR DIAGNOSIS OF MYOCARDIAL-INFARCTION.
OFEGAN, P,ODOHERTY, A,FORDE, T,KANE, M (1995) RAPID LATEX ASSAY OF MYOGLOBIN FOR DIAGNOSIS OF MYOCARDIAL-INFARCTION. Abstract [Details]
(2004) Purification of Adenoviral and Adeno-Associated Viral Vectors using the Membrane-Based Methods of the Adenopure TM Kit and ViraKit. 12th Annual Congress of the ESGT, Tampere, Finland.
Duffy, A, O'Doherty, A, O'Brien, T, Strappe, P (2004) Purification of Adenoviral and Adeno-Associated Viral Vectors using the Membrane-Based Methods of the Adenopure TM Kit and ViraKit. 12th Annual Congress of the ESGT, Tampere, Finland. Abstract [Details]
(2007) AAV-medaited delivery of paraoxonase 1 (PON1) to the apoE-/- mouse as gene therapy for atherosclerosis. 25th Annual Meeting American Society of Gene Therapy, Seattle, USA.
O'Doherty A, Rosenblat M, Aviram M, O'Brien T (2007) AAV-medaited delivery of paraoxonase 1 (PON1) to the apoE-/- mouse as gene therapy for atherosclerosis. 25th Annual Meeting American Society of Gene Therapy, Seattle, USA. Abstract [Details]
(2011) HEAT SHOCK PROTEIN GENE THERAPY IN THE ALPHA-SYNUCLEIN VIRAL GENE TRANSFER RAT MODEL OF PARKINSON'S DISEASE.
Hyland, R,Gorman, AM,O'Doherty, A,Dowd, E (2011) HEAT SHOCK PROTEIN GENE THERAPY IN THE ALPHA-SYNUCLEIN VIRAL GENE TRANSFER RAT MODEL OF PARKINSON'S DISEASE. Abstract [Details]
(2012) Atherosclerotic environment accentuates endochondral ossification in vessel derived stem cells: In vitro and in vivo assessment.
Leszczynska, A,Farrell, E,O'Doherty, A,O'Brien, FJ,O'Brien, T,Barry, FP,Murphy, JM (2012) Atherosclerotic environment accentuates endochondral ossification in vessel derived stem cells: In vitro and in vivo assessment. Abstract [Details]
(2012) OSSIFICATION OF ATHEROSCLEROTIC PLAQUE: THE ROLE OF VESSEL DERIVED STEM CELLS; HEART.
Leszczynska, A,O'Doherty, A,Barry, F,O'Brien, T,Murphy, M (2012) OSSIFICATION OF ATHEROSCLEROTIC PLAQUE: THE ROLE OF VESSEL DERIVED STEM CELLS; HEART. Abstract [Details]
(2014) A comparison of endochondral ossification by vessel-derived and mesenchymal stem cells in wild type and ApoE knockout mice: interleukin 6 as a potential mediator of plaque-associated calcification.
Leszczynska, A,O'Doherty, A,Farrell, E,O'brien, F,O'brien, T,Murphy, M (2014) A comparison of endochondral ossification by vessel-derived and mesenchymal stem cells in wild type and ApoE knockout mice: interleukin 6 as a potential mediator of plaque-associated calcification. Abstract [Details]

Conference Paper

  Year Publication
(2012) Vessel derived stem cells contribute to endochondral ossification of atherosclerotic plaque. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE.
Leszczynska, A,Farrell, E,O'Doherty, A,O'Brien, FJ,O'Brien, T,Barry, FP,Murphy, JM (2012) Vessel derived stem cells contribute to endochondral ossification of atherosclerotic plaque. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE. Conference Paper [Details]

Meeting

  Year Publication
(2011) SYSTEMIC ROTENONE DOES NOT ENHANCE PARKINSONIAN PATHOLOGY CAUSED BY INTRACEREBRAL alpha-SYNUCLEIN IN RATS.
Mulcahy, PJ,O'Doherty, A,O'Brien, T,Kirik, D,Dowd, E (2011) SYSTEMIC ROTENONE DOES NOT ENHANCE PARKINSONIAN PATHOLOGY CAUSED BY INTRACEREBRAL alpha-SYNUCLEIN IN RATS. Meeting [Details]
(2012) ENHANCED ENDOCHONDRAL OSSIFICATION IN VESSEL DERIVED STEM CELLS BY ATHEROSCLEROTIC ENVIRONMENT.
Leszczynsk, A,O'Doherty, A,Farrell, E,O'Brien, F,O'Brien, T,Murphy, M (2012) ENHANCED ENDOCHONDRAL OSSIFICATION IN VESSEL DERIVED STEM CELLS BY ATHEROSCLEROTIC ENVIRONMENT. Meeting [DOI] [Details]