Biological and Chemical Sciences

The Plant Developmental Epigenetics Lab focuses on the critical role of chromatin and epigenetic processes in regulating gene expression and plant development. Through a multidisciplinary approach combining advanced molecular techniques, our lab seeks to elucidate how these chromatin-related and epigenetic processes function and how their activities are coordinated to drive gene expression, ultimately impacting plant growth and development. Our research aligns with global sustainability goals, particularly those related to food security, sustainable agriculture, and climate action.Our work is structured around three main research topics:

1. Identification of New Components of the Polycomb Pathway:
   Polycomb Group (PcG) proteins are essential components of the epigenetic machinery, acting as master regulators of development in both plants and animals. While these proteins are highly conserved across species, plants possess unique developmental needs, leading to the evolution of plant-specific PcG proteins. These proteins play a pivotal role in traits with significant implications for human life, such as flowering and seed development. Our primary goal is to uncover the diversity of PcG complexes that govern specific aspects of plant development by identifying novel PcG components in Arabidopsis thaliana and exploring their molecular functions. This research not only advances our understanding of plant biology but also supports sustainable agriculture by potentially enhancing crop resilience and productivity.
2. Fucoxanthin Production in Diatoms:
   Fucoxanthin, the primary carotenoid produced in brown microalgae, is highly valued in biotechnology due to its numerous health benefits, including antioxidant, anti-tumor, and anti-inflammatory properties. However, the biosynthetic pathway of fucoxanthin, particularly its regulation in response to environmental factors like light, remains incompletely understood. Our project aims to investigate the genetic and epigenetic regulation of fucoxanthin biosynthesis in the model diatom Phaeodactylum tricornutum, with a focus on how light influences production. By identifying key regulatory mechanisms, we hope to develop biotechnological tools to enhance fucoxanthin production, contributing to sustainable practices in health and nutrition industries.
3. Identifying Epigenetic Tools for Seed Vigour:
   Seeds are fundamental to global food security, serving as the primary food source and offering potential as alternatives to petroleum-based fuels. As the global population approaches 9 billion, ensuring robust seed performance is crucial for sustainable agriculture. However, climate change poses significant challenges to seed germination and vigour, especially under abiotic stresses. Our research seeks to identify the epigenetic processes that regulate seed vigour, using Brassica napus (rapeseed) as model crop. By enhancing seed resilience and adaptability to environmental changes, our work contributes directly to the United Nations' Sustainable Development Goals (SDGs), particularly those targeting zero hunger (SDG 2) and climate action (SDG 13).

Overall, the Plant Developmental Epigenetics Lab is committed to advancing knowledge that supports sustainable development and contributes to the resilience of agricultural systems in the face of global challenges.