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Medicine

Dr Siobhan McMahon

B.Sc., Ph.D.

 
researcher
 

Biography

Dr Siobhan McMahon was awarded her B.Sc.(Hons) in Biology from NUI Maynooth in 1994. She was awarded her Ph.D. in 2000 from University College Cork where she investigated the differentiation of radial glial in the developing spinal cord. She continued her research in University College Cork as a postdoctoral research fellow investigating the lineage potential of glial cells in the developing spinal cord. In 2005 she joined REMEDI as a HRB funded postdoctoral fellow. Her research then focused on the use of lentiviral vectors to treat injury in the central nervous system. In November 2006 she joined the Discipline of Anatomy as a lecturer . Her research currently involves use of stem cells, viral vectors and polymer scaffolds to promote regeneration following spinal cord injury.

Research Interests

spinal cord repair, glial scarring, neurotrophic factors, developmental neurobiology, stem cell biology, gene therapy, scaffolds for spinal cord tissue engineering, rnerve regeneration.

Research Projects

  Project Start Date End Date
MOHD NOR AZIM BIN AB PATAR KEMENTERIAN PENGAJIAN TINGGI MALAYSIA FRANK BARRY 01-SEP-12 21-NOV-21
DEVELOPMENT OF A PLATFORM GROWTH ACTOR DELIVERY TECHNOLOGY FROM HYDROGELS MALLINKRODT MED COVIDIEN SIOBHAN MCMAHON BIODELIVERY PROJ PART 2 OF 2 28-SEP-10 30-JUN-14
GENERAL ACCOUNT SIOBHAN MCMAHON 01-DEC-09 30-NOV-22
HRB REGENERATION OF INJURED SPINAL CORD S MCMA 01-AUG-07 31-JUL-10
MF06P34 MILLENNIUM FUND 2006 S MCMAHON 01-JAN-07 09-JUN-09
HRB-siRNA to CNS- RP2005140 S MC MAHON 07-NOV-05 31-MAR-10

Peer Reviewed Journals

  Year Publication
(2022) 'Distinct Glycosylation Responses to Spinal Cord Injury in Regenerative and Nonregenerative Models'
Ronan, R; Kshirsagar, A; Rebelo, AL; Sunny, A; Kilcoyne, M; O¿ Flaherty, R; Rudd, PM; Schlosser, G; Saldova, S; Pandit, A; McMahon, SS (2022) 'Distinct Glycosylation Responses to Spinal Cord Injury in Regenerative and Nonregenerative Models'. Journal Of Proteome Research, 21 (6):1449-1466 [DOI] [Details]
(2023) 'An insight into new glycotherapeutics in glial inflammation: Understanding the role of glycosylation in mitochondrial function and acute to the chronic phases of inflammation'
Patil, V; Bohara, R; Winter, C; Kilcoyne, M; McMahon, S; Pandit, A (2023) 'An insight into new glycotherapeutics in glial inflammation: Understanding the role of glycosylation in mitochondrial function and acute to the chronic phases of inflammation'. Cns Neuroscience & Therapeutics, 29 (1):429-444 [DOI] [Details]
(2011) 'Nano-textured self-assembled aligned collagen hydrogels promote directional neurite guidance and overcome inhibition by myelin associated glycoprotein'
Abu-Rub, MT and Billiar, KL and van Es, MH and Knight, A and Rodriguez, BJ and Zeugolis, DI and McMahon, S and Windebank, AJ and Pandit, A (2011) 'Nano-textured self-assembled aligned collagen hydrogels promote directional neurite guidance and overcome inhibition by myelin associated glycoprotein'. Soft Matter, 7 (6):2770-2781 [Details]
(2021) 'Lentiviral Vectors Delivered with Biomaterials as Therapeutics for Spinal Cord Injury'
Shortiss, C; Howard, L; McMahon S (2021) 'Lentiviral Vectors Delivered with Biomaterials as Therapeutics for Spinal Cord Injury'. Cells, [DOI] [Details]
(2019) 'Differential Glycosylation Expression in Injured Rat Spinal Cord Treated with Immunosuppressive Drug Cyclosporin-A'
Kilcoyne M;Patil V;O'Grady C;Bradley C;McMahon SS; (2019) 'Differential Glycosylation Expression in Injured Rat Spinal Cord Treated with Immunosuppressive Drug Cyclosporin-A'. Acs Omega, 4 (2) [DOI] [ARAN Link] [Details]
(2021) 'A Robust Platform for High-throughput Screening of Therapeutic Strategies for Acute and Chronic Spinal Cord Injury'
Patil V; O'Connell E; Quinlan L; Fearnhead H; McMahon S; Pandit A (2021) 'A Robust Platform for High-throughput Screening of Therapeutic Strategies for Acute and Chronic Spinal Cord Injury'. Iscience, [Details]
(2020) 'Ex Vivo Rat Transected Spinal Cord Slices as a Model to Assess Lentiviral Vector Delivery of Neurotrophin-3 and Short Hairpin RNA against NG2'
Patar A;Dockery P;McMahon S;Howard L; (2020) 'Ex Vivo Rat Transected Spinal Cord Slices as a Model to Assess Lentiviral Vector Delivery of Neurotrophin-3 and Short Hairpin RNA against NG2'. Biology, 9 (3) [DOI] [Details]
(2018) 'GDNF Schwann cells in hydrogel scaffolds promote regional axon regeneration, remyelination and functional improvement after spinal cord transection in rats'
Chen, BK,Madigan, NN,Hakim, JS,Dadsetan, M,McMahon, SS,Yaszemski, MJ,Windebank, AJ (2018) 'GDNF Schwann cells in hydrogel scaffolds promote regional axon regeneration, remyelination and functional improvement after spinal cord transection in rats'. Journal Of Tissue Engineering And Regenerative Medicine, 12 :398-407 [DOI] [ARAN Link] [Details]
(2019) 'Analysis of reactive astrocytes and NG2 proteoglycan in ex vivo rat models of spinal cord injury'
Patar, A,Dockery, P,Howard, L,McMahon, S (2019) 'Analysis of reactive astrocytes and NG2 proteoglycan in ex vivo rat models of spinal cord injury'. Journal Of Neuroscience Methods, 311 :418-425 [DOI] [ARAN Link] [Details]
(2019) 'Cell viability in three ex vivo rat models of spinal cord injury'
Patar, A,Dockery, P,Howard, L,McMahon, SS (2019) 'Cell viability in three ex vivo rat models of spinal cord injury'. Journal Of Anatomy, 234 :244-251 [DOI] [ARAN Link] [Details]
(2017) 'Therapeutic Effect of Neurotrophin-3 Treatment in an Injectable Collagen Scaffold Following Rat Spinal Cord Hemisection Injury'
Breen, BA,Kraskiewicz, H,Ronan, R,Kshiragar, A,Patar, A,Sargeant, T,Pandit, A,McMahon, SS (2017) 'Therapeutic Effect of Neurotrophin-3 Treatment in an Injectable Collagen Scaffold Following Rat Spinal Cord Hemisection Injury'. ACS Biomaterials Science & Engineering, 3 :1287-1295 [DOI] [ARAN Link] [Details]
(2016) 'NON-VIRAL XYLOSYLTRANSFERASE-1 siRNA DELIVERY AS AN EFFECTIVE ALTERNATIVE TO CHONDROITINASE IN AN IN VITRO MODEL OF REACTIVE ASTROCYTES'
Abu-Rub, MT,Newland, B,Naughton, M,Wang, WX,Mcmahon, S,Pandit, A (2016) 'NON-VIRAL XYLOSYLTRANSFERASE-1 siRNA DELIVERY AS AN EFFECTIVE ALTERNATIVE TO CHONDROITINASE IN AN IN VITRO MODEL OF REACTIVE ASTROCYTES'. Neuroscience, 339 :267-275 [DOI] [ARAN Link] [Details]
(2014) 'Comparison of Cellular Architecture, Axonal Growth, and Blood Vessel Formation Through Cell-Loaded Polymer Scaffolds in the Transected Rat Spinal Cord'
Madigan, NN,Chen, BK,Knight, AM,Rooney, GE,Sweeney, E,Kinnavane, L,Yaszemski, MJ,Dockery, P,O'Brien, T,McMahon, SS,Windebank, AJ (2014) 'Comparison of Cellular Architecture, Axonal Growth, and Blood Vessel Formation Through Cell-Loaded Polymer Scaffolds in the Transected Rat Spinal Cord'. Tissue Engineering Part A, 20 :2985-2997 [DOI] [ARAN Link] [Details]
(2013) 'Assembly of Protein-based Hollow Spheres Encapsulating a Therapeutic Factor'
Kraskiewicz H, Breen B, Sargeant T, McMahon S, Pandit A (2013) 'Assembly of Protein-based Hollow Spheres Encapsulating a Therapeutic Factor'. Acs Chemical Neuroscience, [DOI] [ARAN Link] [Details]
(2012) 'Lentiviral vector delivery of short hairpin RNA to NG2 and neurotrophin-3 promotes locomotor recovery in injured rat spinal cord'
Donnelly EM, Madigan NN, Rooney GE, Knight A, Chen B, Ball B, Kinnavane L, Garcia Y, Dockery P, Fraher J, Strappe PM, Windebank AJ, O'Brien T, McMahon SS (2012) 'Lentiviral vector delivery of short hairpin RNA to NG2 and neurotrophin-3 promotes locomotor recovery in injured rat spinal cord'. Cytotherapy, 14 (10):1235-1244 [DOI] [Details]
(2012) 'Neuronal glycosylation differentials in normal, injured and chondroitinase-treated environments'
Kilcoyne, M,Sharma, S,McDevitt, N,O'Leary, C,Joshi, L,McMahon, SS (2012) 'Neuronal glycosylation differentials in normal, injured and chondroitinase-treated environments'. Biochemical And Biophysical Research Communications, 420 :616-622 [DOI] [ARAN Link] [Details]
(2011) 'Thermosensitive hydrogel for prolonged delivery of lentiviral vector expressing neurotrophin-3 in vitro'
McMahon, SS,Nikolskaya, N,Choileain, SN,Hennessy, N,O'Brien, T,Strappe, PM,Gorelov, A,Rochev, Y (2011) 'Thermosensitive hydrogel for prolonged delivery of lentiviral vector expressing neurotrophin-3 in vitro'. Journal Of Gene Medicine, 13 :591-601 [DOI] [ARAN Link] [Details]
(2010) 'Engraftment, migration and differentiation of neural stem cells in the rat spinal cord following contusion injury'
McMahon, SS,Albermann, S,Rooney, GE,Shaw, G,Garcia, Y,Sweeney, E,Hynes, J,Dockery, P,O'Brien, T,Windebank, AJ,Allsopp, TE,Barry, FP (2010) 'Engraftment, migration and differentiation of neural stem cells in the rat spinal cord following contusion injury'. Cytotherapy, 12 :313-325 [DOI] [ARAN Link] [Details]
(2009) 'Neurotrophic Factor-Expressing Mesenchymal Stem Cells Survive Transplantation into the Contused Spinal Cord Without Differentiating into Neural Cells'
Rooney, GE,McMahon, SS,Ritter, T,Garcia, Y,Moran, C,Madigan, NN,Flugel, A,Dockery, P,O'Brien, T,Howard, L,Windebank, AJ,Barry, FP (2009) 'Neurotrophic Factor-Expressing Mesenchymal Stem Cells Survive Transplantation into the Contused Spinal Cord Without Differentiating into Neural Cells'. Tissue Engineering Part A, 15 :3049-3059 [DOI] [ARAN Link] [Details]
(2009) 'Analysis of cellular environment of spinal cord lesion following transplantation of neural stem cells into injured rat spinal cord'
Hynes, J.,Bourke, E.,Deering, E. M.,Doherty, G.,Murray, A.,Dockery, P.,Doyle, K.,Gorman, A.,Barry, F. P.,McMahon, S. S. (2009) 'Analysis of cellular environment of spinal cord lesion following transplantation of neural stem cells into injured rat spinal cord'. Journal of Anatomy, 214 (55):793-793 [Details]
(2009) 'Effect of cyclosporin A on functional recovery in the spinal cord following contusion injury'
McMahon SS, Albermann S, Rooney GE, Moran C, Hynes J, Garcia Y, Dockery P, O'Brien T, Windebank AJ, Barry FP (2009) 'Effect of cyclosporin A on functional recovery in the spinal cord following contusion injury'. Journal Of Anatomy, 215 (3):267-279 [DOI] [Details]
(2008) 'Gene-modified mesenchymal stem cells express functionally active nerve growth factor on an engineered poly lactic glycolic acid (PLGA) substrate'
Rooney, GE,Moran, C,McMahon, SS,Ritter, T,Maenz, M,Flugel, A,Dockery, P,O'Brien, T,Howard, L,Windebank, AJ,Barry, FP (2008) 'Gene-modified mesenchymal stem cells express functionally active nerve growth factor on an engineered poly lactic glycolic acid (PLGA) substrate'. Tissue Engineering Part A, 14 :681-690 [DOI] [Details]
(2003) 'Estimation of nuclear volume as an indicator of maturation of glial precursor cells in the developing rat spinal cord: a stereological approach'
McMahon SS, Dockery P, McDermott KW (2003) 'Estimation of nuclear volume as an indicator of maturation of glial precursor cells in the developing rat spinal cord: a stereological approach'. Journal Of Anatomy, 203 (3):339-344 [Details]
(2002) 'Morphology and differentiation of radial glia in the developing rat spinal cord'
McMahon, SS,McDermott, KW (2002) 'Morphology and differentiation of radial glia in the developing rat spinal cord'. J Comp Neurol, 454 :263-271 [DOI] [Details]
(2001) 'Proliferation and migration of glial precursor cells in the developing rat spinal cord'
McMahon, SS,McDermott, KW (2001) 'Proliferation and migration of glial precursor cells in the developing rat spinal cord'. Journal Of Neurocytology, 30 :821-828 [Details]
(2005) 'Role of radial glia in cytogenesis, patterning and boundary formation in the developing rat spinal cord'
McDermott K.W., Barry D.S. & McMahon S.S. (2005) 'Role of radial glia in cytogenesis, patterning and boundary formation in the developing rat spinal cord'. JOURNAL OF ANATOMY, 207 :241-250 [Details]
(2006) 'A comparison of cell transplantation and retroviral gene transfection as tools to study lineage and differentiation in the rat spinal cord'
McMahon, SS,McDermott, KW (2006) 'A comparison of cell transplantation and retroviral gene transfection as tools to study lineage and differentiation in the rat spinal cord'. Journal Of Neuroscience Methods, 152 :243-249 [DOI] [Details]
(2007) 'Developmental potential of radial glia investigated by transplantation into the developing rat ventricular system in utero'
McMahon, SS,McDermott, KW (2007) 'Developmental potential of radial glia investigated by transplantation into the developing rat ventricular system in utero'. Experimental Neurology, 203 :128-136 [DOI] [Details]
(2009) 'Current tissue engineering and novel therapeutic approaches to axonal regeneration following spinal cord injury using polymer scaffolds'
Madigan NN, McMahon S, O'Brien T, Yaszemski MJ, Windebank AJ. (2009) 'Current tissue engineering and novel therapeutic approaches to axonal regeneration following spinal cord injury using polymer scaffolds'. Respiratory Medicine, 169 (2):183-199 [Details]
(2010) 'Spinal cord injury in vitro: modelling axon growth inhibition. '
Abu-Rub M, McMahon S, Zeugolis DI, Windebank A, Pandit A.  (2010) 'Spinal cord injury in vitro: modelling axon growth inhibition. '. Drug Discov Today, 15 (11-12):436-443 [Details]

Book Chapters

  Year Publication
(2021) 'Lectin Histochemistry for Tissues and Cells, and Dual Lectin and Antibody Co-localization'
Siobhán S. McMahon and Michelle Kilcoyne (2021) 'Lectin Histochemistry for Tissues and Cells, and Dual Lectin and Antibody Co-localization' In: Part of the Methods in Molecular Biology book series. Humana Press: Springer protocols. [Details]

Conference Publications

  Year Publication
(2016) Neuroscience Ireland Young Neuroscientists Meeting
Patil, V., McMahon, S. and Pandit, A. (2016) Primary Mix Glial Culture from Spinal Cord Inflamed by Pro-Inflammatory Cytokines is a Valid Model of Inflammation after Spinal Cord Injury Neuroscience Ireland Young Neuroscientists Meeting [Details]

Abstract

  Year Publication
(2017) Cellular and glycomic facilitators of regeneration in a Xenopus laevis model of spinal cord injury. Neuroscience Conference Ireland, Galway, Ireland, 28.-29.8.2017.
Ronan, R., Kshirsagar, A., Rebelo, A.L., Kilcoyne, M., Schlosser, G., Pandit, A., McMahon, S. (2017) Cellular and glycomic facilitators of regeneration in a Xenopus laevis model of spinal cord injury. Neuroscience Conference Ireland, Galway, Ireland, 28.-29.8.2017. Abstract [Details]
(2017) Molecular Mechanisms of Spinal Cord Regeneration in Xenopus Laevis. 4th internationsl spinal cord repair meeting (ISCORE 2017), Barcelona, Spain, 3.-4.11.2017.
Kshirsagar, A., Ronan, R., Rebelo, A.L., Schlosser, G., McMahon, S., Pandit, A. (2017) Molecular Mechanisms of Spinal Cord Regeneration in Xenopus Laevis. 4th internationsl spinal cord repair meeting (ISCORE 2017), Barcelona, Spain, 3.-4.11.2017. Abstract [Details]
(2017) Glycosylation changes in the injured and regenerating spinal cord of Xenopus laevis. Matrix Biology Ireland, Trinity College Dublin, 30.11.-1.12.2017.
Ronan, R., Kshirsagar, A., Kilcoyne, M., Schlosser, G., Pandit, A., McMahon, S. (2017) Glycosylation changes in the injured and regenerating spinal cord of Xenopus laevis. Matrix Biology Ireland, Trinity College Dublin, 30.11.-1.12.2017. Abstract [Details]
(2018) Glycobiological and glial regulation of the regenerative process following spinal cord injury, and the influence of biomaterial treatment. Gordon Research Conference „Neurobiology of Brain Disorders“ Castelldefels, Spain, 5.-10.8.2018.
Ronan, R., Kshirsagar, A., Kilcoyne, M., Schlosser, G., O’Flaherty, R., Saldova, R., Pandit, A., McMahon, S. (2018) Glycobiological and glial regulation of the regenerative process following spinal cord injury, and the influence of biomaterial treatment. Gordon Research Conference „Neurobiology of Brain Disorders“ Castelldefels, Spain, 5.-10.8.2018. Abstract [Details]
(2018) Molecular mechanisms of spinal cord regeneration in Xenopus. EMBO workshop “The molecular and cellular basis of regeneration and tissue repair”. Valetta, Malta, 15.-19.9.2018.
Kshirsagar, A., Ronan, R., Rebelo, A.L., McMahon, S., Schlosser, G., Pandit, A. (2018) Molecular mechanisms of spinal cord regeneration in Xenopus. EMBO workshop “The molecular and cellular basis of regeneration and tissue repair”. Valetta, Malta, 15.-19.9.2018. Abstract [Details]
(2017) Glycobiology of spinal cord injury. .
Ronan, R; Kshirsagar, A; Kilcoyne, M; O’Flaherty, R; Saldova, R; Schlosser, G; Pandit, A; McMahon, S (2017) Glycobiology of spinal cord injury. . 19th European Carbohydrate Symposium (Eurocarb), Barcelona, Spain, 2.-6.7.2017: Abstract [Details]
(2016) Standardisation of Xenopus laevis spinal cord injury model for identification of proteins associated with spinal cord regeneration using iTRAQ based MS.
Kshirsagar, A; Ronan, R; Rebelo, AL; McMahon, S; Schlosser, G; Pandit, A (2016) Standardisation of Xenopus laevis spinal cord injury model for identification of proteins associated with spinal cord regeneration using iTRAQ based MS. FENS Forum of Neuroscience, Copenhagen, Denmark, 2.-6.7.2016: Abstract [Details]
(2015) Development of Xenopus laevis as a model to study spinal cord regeneration.
Kshirsagar, A; Ronan, R; Rebelo, AL; Rink, E; McMahon, S; Schlosser, G; Pandit, A (2015) Development of Xenopus laevis as a model to study spinal cord regeneration. 9th Neuroscience Ireland Conference, Dublin, 1.-2.9.2015: Abstract [Details]
(2015) Glycobiology of the spinal cord in tadpole Xenopus laevis.
Ronan, R; Kshirsagar, A; Joshi, L; Kilcoyne, M; Schlosser, G; Pandit, A; McMahon, S (2015) Glycobiology of the spinal cord in tadpole Xenopus laevis. Annual Symposium of the Microscopy Society of Ireland, Limerick, 26.-28.8.2015: Abstract [Details]
(2007) Analysis of cellular environment of the injured rat spinal cord following treatment with cyclosporin A.
McMahon, S,Brennan, S,Kelly, J,O'Brien, L,Ryan, E,Dockery, P,Rooney, G,Moran, C,Windebank, A,Barry, F (2007) Analysis of cellular environment of the injured rat spinal cord following treatment with cyclosporin A. Abstract [Details]
(2008) An ultrastructural study of the effect of silencing NG2 inhibitory factor.
McMahon, S,Dockery, P,Donnelly, E,Fraher, J,Strappe, P,O'Brien, T (2008) An ultrastructural study of the effect of silencing NG2 inhibitory factor. Abstract [Details]
(2009) AN ASTROCYTE-DORSAL ROOT GANGLION CO-CULTURE MODEL TO ASSESS NEURITE OUTGROWTH FROM LENTIVIRAL VECTOR EXPRESSED NEUROTROPHIN-3.
McMahon, S,Rooney, G,Donnelly, E,O'Brien, T,Fraher, J,Windebank, A,Dockery, P,Hampton, D,Strappe, P (2009) AN ASTROCYTE-DORSAL ROOT GANGLION CO-CULTURE MODEL TO ASSESS NEURITE OUTGROWTH FROM LENTIVIRAL VECTOR EXPRESSED NEUROTROPHIN-3. Abstract [Details]

Conference Poster

  Year Publication
(2007) Effect of lentiviral vector expressing neurotrophin-3 on neurite outgrowth following spinal cord injury. Irish Society for Gene and Cell Therapy Meeting Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway.
McMahon S.S., Donnelly E., Fraher J.P., Dockery P., O'Brien T., Strappe P. (2007) Effect of lentiviral vector expressing neurotrophin-3 on neurite outgrowth following spinal cord injury. Irish Society for Gene and Cell Therapy Meeting Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway. Conference Poster [Details]
(2007) Analysis of the Effect of Cyclosporin A on the Cellular Environment of the Injured Rat Spinal Cord. Irish Society for Gene and Cell Therapy Meeting Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway.
Siobhan McMahon, Siobhan Brennan, Johanne Kelly, Laura O'Brien, Éanna Ryan, Peter Dockery, Gemma Rooney, Cathal Moran, Anthony Windebank, Frank Barry. (2007) Analysis of the Effect of Cyclosporin A on the Cellular Environment of the Injured Rat Spinal Cord. Irish Society for Gene and Cell Therapy Meeting Regenerative Medicine Institute (REMEDI), National University of Ireland, Galway. Conference Poster [Details]
(2008) Effect of lentiviral vector expressing Neurotrophin-3 and shRNA for NG2 on cellular environment of injured spinal cord. ESGCT meeting Brugge.
Eleanor Donnelly, Siobhan McMahon, Peter Dockery, John Fraher, Padraig Strappe, Daniel O'Toole, Lisa McGinley, Timothy O'Brien. (2008) Effect of lentiviral vector expressing Neurotrophin-3 and shRNA for NG2 on cellular environment of injured spinal cord. ESGCT meeting Brugge. Belgium: Conference Poster [Details]
(2008) Thermosensitive Hydrogel For Prolonged Lentivirus Delivery. Neuroscience Ireland Meeting.
S.McMahon, N Nikolskaya, S. Ní Choileán, N. Hennessy, Y. Rochev. (2008) Thermosensitive Hydrogel For Prolonged Lentivirus Delivery. Neuroscience Ireland Meeting. NUI Galway: Conference Poster [Details]
(2008) Regeneration Of Injured Spinal Cord Neurons Through Implantable Polymer Bridges Using A Combined Approach Of Neurotrophic Support And Glial Scar Inhibition.. Neuroscience Ireland Meeting NUI.
N. Madigan, G. Rooney, T. Ritter, F. Barry, A. Windebank, T. O'Brien, S. McMahon. (2008) Regeneration Of Injured Spinal Cord Neurons Through Implantable Polymer Bridges Using A Combined Approach Of Neurotrophic Support And Glial Scar Inhibition.. Neuroscience Ireland Meeting NUI. Galway: Conference Poster [Details]
(2008) Neural stem cells reduce apoptosis following transplantation into injured rat spinal cord.. Neuroscience Ireland Meeting NUI Galway.
Jacqueline Hynes, Elaine Bourke, Eoin McCarthy Deering, Graham Doherty, Andrea Murray, Peter Dockery, Karen Doyle, Adrienne Gorman, Timothy Allsopp, Frank P. Barry, Siobhan S. McMahon. (2008) Neural stem cells reduce apoptosis following transplantation into injured rat spinal cord.. Neuroscience Ireland Meeting NUI Galway. Conference Poster [Details]
(2008) Analysis of Neural Stem Cells Following Transplantation into Injured Rat Spinal Cord. Irish Society for Gene and Cell Therapy Meeting University College Cork.
Siobhan S. McMahon, Silke Albermann , Gemma E. Rooney, Timothy O'Brien, Yolanda Garcia, Peter Dockery, Anthony J. Windebank, Timothy E. Allsopp, Frank P. Barry. (2008) Analysis of Neural Stem Cells Following Transplantation into Injured Rat Spinal Cord. Irish Society for Gene and Cell Therapy Meeting University College Cork. Conference Poster [Details]
(2008) Silencing Ng2 Inhibitory Factor And Its Effect On Dorsal Root Ganglia Neurite Outgrowth. Neuroscience Ireland Meeting NUI.
Eleanor Donnelly, Lisa Mcginley, Peter Dockery, John Fraher, Padraig Strappe, Daniel O'Toole, Nicolas Madigan, Gemma Rooney, Timothy O'Brien, Siobhan McMahon. (2008) Silencing Ng2 Inhibitory Factor And Its Effect On Dorsal Root Ganglia Neurite Outgrowth. Neuroscience Ireland Meeting NUI. Galway: Conference Poster [Details]
(2008) Analysis Of Neuron Cell Surface Glycosylation Differentials In A Chondroitin Sulphate Proteoglycan Inhibitory Environment. Neuroscience Ireland Meeting NUI Galway.
Claire O'Leary, Michelle Kilcoyne, Lokesh Joshi, Peter Dockery, Siobhan McMahon. (2008) Analysis Of Neuron Cell Surface Glycosylation Differentials In A Chondroitin Sulphate Proteoglycan Inhibitory Environment. Neuroscience Ireland Meeting NUI Galway. Conference Poster [Details]
(2008) Silencing NG2 inhibitory factor and its effect on dorsal root ganglia neurite outgrowth. Irish Society for Gene and Cell Therapy Meeting University College Cork.
Eleanor Donnelly, Siobhan McMahon, Peter Dockery, John Fraher, Padraig Strappe, Daniel O'Toole, Lisa Mcginley, Timothy O'Brien. (2008) Silencing NG2 inhibitory factor and its effect on dorsal root ganglia neurite outgrowth. Irish Society for Gene and Cell Therapy Meeting University College Cork. Conference Poster [Details]
(2008) Analysis of Neural Stem Cells Following Transplantation into Injured Rat Spinal Cord. Neuroscience Ireland Meeting.
Siobhan S. McMahon, Silke Albermann, Gemma E. Rooney, Timothy O'Brien, Yolanda Garcia, Peter Dockery, Anthony J. Windebank, Timothy E. Allsopp, Frank P. Barry. (2008) Analysis of Neural Stem Cells Following Transplantation into Injured Rat Spinal Cord. Neuroscience Ireland Meeting. NUI Galway: Conference Poster [Details]
(2008) Analysis of Cellular Environment of Spinal Cord Lesion Following Transplantation of Neural Stem Cells into Injured Rat Spinal Cord. Meeting of the Anatomical Society of Great Britain and Ireland Nottingham.
Jacqueline Hynes, Elaine Bourke, Eoin McCarthy Deering, Graham Doherty, Andrea Murray, Peter Dockery, Karen Doyle, Adrienne Gorman, Frank P. Barry, Siobhan S. McMahon. (2008) Analysis of Cellular Environment of Spinal Cord Lesion Following Transplantation of Neural Stem Cells into Injured Rat Spinal Cord. Meeting of the Anatomical Society of Great Britain and Ireland Nottingham. Conference Poster [Details]
(2007) Efficiency of lentiviral vector transduction in injured rat spinal cord. A stereological analysis. Meeting of the Anatomical Society of Great Britain and Ireland.
Toal F., Donnelly E., O'Brien T., Kelly J.P., Fraher J.P., Strappe P., Dockery P., McMahon S.S. (2007) Efficiency of lentiviral vector transduction in injured rat spinal cord. A stereological analysis. Meeting of the Anatomical Society of Great Britain and Ireland. Durham: Conference Poster [Details]
(2007) Analysis of Cellular Environment of the Injured Rat Spinal Cord following Treatment with Cyclosporin. 8th European meeting on glial cell function in health and disease London.
A. Siobhan McMahon, Siobhan Brennan, Johanne Kelly, Laura O'Brien, Éanna Ryan, Peter Dockery, Gemma Rooney, Cathal Moran, Anthony Windebank, Frank Barry. (2007) Analysis of Cellular Environment of the Injured Rat Spinal Cord following Treatment with Cyclosporin. 8th European meeting on glial cell function in health and disease London. Conference Poster [Details]
(2007) Effect of Lentiviral Vector Expressing Neurotrophin-3 on Dorsal Root Ganglia Neurite Outgrowth. 8th European meeting on glial cell function in health and disease London.
Donnelly E., McMahon S.S., Strappe P, Rooney G., Fraher J.P., Dockery P., O'Brien T. (2007) Effect of Lentiviral Vector Expressing Neurotrophin-3 on Dorsal Root Ganglia Neurite Outgrowth. 8th European meeting on glial cell function in health and disease London. Conference Poster [Details]
(2008) Glial-Derived Neurotrophic Factor–Expressing Mesenchymal Stem Cells Survive Transplantation into the Contused Spinal Cord without Differentiating into Neural Cells. SFN Meeting.
Gemma E. Rooney, Siobhan S. McMahon, Thomas Ritter, Yolanda Garcia, Nicolas Madigan, Alexander Flügel, Kim K. Nickander, Peter Dockery, Timothy O'Brien, Linda Howard, Anthony J. Windebank and Frank P. Barry. (2008) Glial-Derived Neurotrophic Factor–Expressing Mesenchymal Stem Cells Survive Transplantation into the Contused Spinal Cord without Differentiating into Neural Cells. SFN Meeting. San Diego: Conference Poster [Details]

Invited papers

  Year Publication
(2007) Gene and stem cell therapy approaches to treatment of spinal cord injury. Invited speaker. Irish Network for Neural Stem Cell Investigators Trinity College, Dublin.
McMahon, S. (2007) Gene and stem cell therapy approaches to treatment of spinal cord injury. Invited speaker. Irish Network for Neural Stem Cell Investigators Trinity College, Dublin. Invited papers [Details]

Reviews

  Year Publication
(2010) Spinal cord injury in vitro: modelling axon growth inhibition.
Abu-Rub, M;McMahon, S;Zeugolis, DI;Windebank, A;Pandit, A (2010) Spinal cord injury in vitro: modelling axon growth inhibition. OXFORD: ELSEVIER SCI LTD Reviews [DOI] [Details]

Workshops

  Year Publication
(2008) Effect of Neural Stem Cells on Spinal Cord Contusion injury. 12th Annual Hilton Head Workshop entitled, Regenerative Medicine: Advancing to Next Generation Therapies Hilton Head, South Carolina, U.S.A.
McMahon, S. (2008) Effect of Neural Stem Cells on Spinal Cord Contusion injury. 12th Annual Hilton Head Workshop entitled, Regenerative Medicine: Advancing to Next Generation Therapies Hilton Head, South Carolina, U.S.A. Workshops [Details]

Honours and Awards

  Year Title Awarding Body
Awarded EMBO Short Term Fellowship

Professional Associations

  Association Function From / To
Anatomical Society of Great Britain and Ireland Member /
European Society of Gene and Cell Therapy Member /
Neuroscience Ireland Member /
British Neuroscience Association Member /
Tissue Engineering and Regenerative Medicine Society Member /
Federation of European Neuroscience Societies Member /
Society for Neuroscience Member /

Recent Postgraduate Students

  Graduation Name Degree Primary Supervisor
2012 Nicolas Madigan PhD Y
2010 Eleanor Donnelly PhD Y