Basic Scientific Research

Overview

The basic scientific research is currently focused on two major areas. The first area of investigation focuses on the pathogenesis of, and potential therapeutic strategies for Acute Lung Injury and ARDS, a key cause of death in severely ill patients. A key long-term aim of this research strand is to develop into a core component of the University's focus on the potential applications of Somatic Gene Therapy to the therapy of diverse medical disease processes. The second area of investigation focuses cardiovascular research, with projects investigating the effects and mechanisms of action of sepsis on the myocardium and on the effects of drugs in the foetal-placental circulation.

Clinical and Translational Research Activities

Overview

The Department is centrally involved in clinical research. Specific areas of focus in clinical research have been identified, focusing on the research interests and expertise of members of the Department. The major clinical research strands include Regional Anaesthesia, and the assessment of the utility of novel airway devices. Additional clinical research projects are encouraged, including the reporting of medical cases of unusual interest [i.e. case reports], and the conduct of audit projects and randomised clinical trials, in areas including obstetrics, ambulatory anaesthesia and intensive care medicine.

Clinical Strand 1 – Acute Perioperative Pain.

Clinical Strand 2 – Evaluation of Airway and Ventilation Devices. 

Clinical Research Team

  • Dr. John McDonnell  Leader, Regional Anaesthesia Research 
  • Prof. John G. Laffey  Leader, Airway and Ventilation Research
  • Dr. Olivia Finnerty, Graduate (MD) Student, Regional Anaesthesia
  • Dr. Anwar Malik, Graduate (MD) Student, Airway Programme

In addition, the Department has identified specific Clinicians with interests, expertise and track records in specific clinical areas. These identified areas of specialisation comprise:

  • Intensive Care Medicine - Prof. Laffey/Dr. Bates
  • Regional Anaesthesia - Dr. McDonnell/Dr. Kinirons
  • Obstetrical Anaesthesia - Dr. Sharkey/Prof. Laffey
  • Hyperbaric Medicine - Dr. Flynn/Dr. Whyte
  • Pain Medicine - Dr. O’ Gorman
  • Ambulatory Anaesthesia - Dr. Grady/Dr. McDonnell

The role of these clinicians is to act as mentors to trainees wishing to pursue research projects in these clinical areas.

Each nominated clinician will undertake responsibility for all aspects of research projects within their area of expertise.