Previous Seminar Speakers

      2022/2023

Speaker

Affiliation 

Topic

Prof Triona Ni Chonghalie

RCSI, Dublin

Harnessing the rubbish bin to kill cancer cells

Prof Eric Brown

University of Pennsylvania, USA

Putting cancer in the crossfire of DDR inhibition

Prof Joanna McGouran

TC Dublin

Proteins and DNA-new tools through chemical modification

Prof Dave Finn

University of Galway

Reciprocal interactions between pain and negative affect: From proteins to pathways to patients

Prof Daniele Fachinetti

Institute Marie Curie, Paris, France

From secondary structures to DNA replication: mechanism that control genome integrity at human centromeres

Dr. Felix Prado 

Andalusian Molecular Biology and Regenerative Medicine Centre, Spain 

DNA damage tolerance mechanisms to ensure DNA replication and genome integrity

Dr. Susana Godinho

BARTS Cancer Institute, Centre for Cancer Cell and Molecular Biology, London UK 

Centrosome amplification and cancer: reaching out

Prof Georg Dechant

Innsbruck University, Austria

SATB2 organizes the 3D genome architecture of cognition in cortical neurons

Prof Teresa Lamb

Jenner Institute, Oxford University, UK

Covid-19 Vaccines: Lessons Learnt

Dr Gideon Coster

The Institute of Cancer Research, London, UK

When DNA becomes its own enemy: The mechanism of DNA-induced replication stalling

Dr Marisa M. Merino

University of Geneva, Switzerland

Breaking Down Growth during Tumorigenesis

Prof Andrea Musacchio

Max Planck Institute Dortmund, Germany

Towards the biochemical reconstitution of eukaryotic cell division

Prof Patrick Sung

University of Texas, San Antonio, USA

The BRCA Axis of DNA Damage Repair and replication Fork Preservation 

 2021/2022

Speaker

Affiliation

Topic

John Dalton

NUI Galway

Malaria: targeting the parasite in the red blood cells 

Peter Crowley      

NUI Galway

Macrocycle-mediated protein assembly

Adrian Bracken

Trinity College Dublin

Polycomb repressive complexes in Cancer and Developmental disorders 

Katarzyna Whysall 

NUI Galway

microRNA's as key regulator of muscle wasting in ageing and disease 

Liam Faller

Netherlands Cancer Institute 

Ribosomes - more than just gene machines 

Yehu Moran 

Hebrew University Jerusalem, Israel

The cnidarian antiviral immune system reflects ancestral complexity. 

Corrado Santocanale

NUI Galway

Blocking DNA synthesis before it begins: insights into CDC7 targeting drugs using functional genomics approaches 

Helle Ulrick

University of Mainz, Germany 

Mind the gap - sensing and processing DNA damage during genome replication. 

Ludovic Orlando

Université Paul Sabatier, Toulouse, France

The genomic history of the modern domestic horse

2020/2021

Speaker

Affiliation

Topic

Ingrid Tessmer

 U. Wuerzburg

Alkyltransferase-like protein clusters scan DNA rapidly over long distances and recruit Nucleotide Excision Repair to alkyl-DNA lesions

Kumar Somyajit

U. Copenhagen

Dynamic coupling between metabolic signalling and DNA replication

Jordi Solana

Oxford Brooks

Using single-cell analysis and planarians to study stem cells, their differentiation and their evolution

Yukiko Yamashita

MIT

Function of junk: satellite DNA in Drosophila spermatogenesis

Julian Sale

MRC LMB Cambridge

Sequences that stall replication

Elsa Logarinho

i3S/ IBMC Porto

Inhibition of age-associated genomic instability: emerging strategy to delay cellular senescence and aging

Tom Williams

 U. Helsinki

Regulation of mammalian mitochondrial destruction by mitophagy

Titia Sixma

NKI Amsterdam

Stepping through DNA mismatch repair initiation

Simona Polo

 IFOM/ FIRC Milan

Ubiquitin HECT E3 ligases: A tale with multiple facets

Mark van Breugel

QMUL

The centriolar CEP164-TTBK2 complex in health and in disease

Kok-Lung Chan

 U.Sussex

The importance of replication machinery control for mitotic chromosome stability

Suliana Manley

 EPFL

Superresolution microscopy reveals organelle organization and dynamics

2019/2020

Speaker

Affiliation

Topic

Colm O Dushlaine

Regeneron Genetics New York

Large-scale genomics as an aide to drug discovery.

Veit Goder

 Universitty of Seville

Protein quality control in the endoplasmic reticulum

Karen Keeshan

Leukaemia Research Centre Glasgow

Therapeutic approaches in acute myeloid leukaemia

Vivek Malhotra

 Centre for Genomic Regulation, Barcelona

Collagen secretion in health, cylindromas, fibrosis and other collagenopathies

Rick Livesey

 University College London

Deciphering dementia with human stem cell systems

Ross Chapman

  Oxford University

Exploiting centrosome dysfunction to kill 17q23 amplified breast cancer cells

Lesley Jones

 Cardiff University

Genetic modifiers in Huntington's disease: an expanding tale

Derek Blake

 Cardiff University

Brain disorders: genome-wide association studies (GWAS) to biology

Alexandre Mirnov

Istituto FIRC di Oncologia Molecolare (IFOM) Milan

Correlative and other methods of modern electron microscopy. Implications for intracellular transport and cytokinesis.

Philippe Pasero

 IGH, University of Montpellier

Spontaneous replication stress as a source of genomic instability and inflammation in cancer

 Jessica Downs

Institute of Cancer Research, London

Loss of SWI/SNF activity and its impact on aneuploidy

 Stefan Knapp

 University of Frankfurt

Selective targeting of kinase catalytic and scaffolding function

Francis Barr

University of Oxford

Temporal and spatial regulation of human cell division by protein phosphatase

Andrei Budanov

 TCD

Sestrins- the guards on crossroads of the DNA-damage response and nutrient sensing

2018/2019

Speaker

Affiliation

Topic

Stefan Marciniak

Cambridge University

The role of endoplasmic reticulum microviscosity in alpha1-antitrypsin deficiency

Pavel Baranov   

 UCC

Genetic decoding diversity: from single genes to the entire genetic codes

Hans-Dieter Volk

Charité/ Berlin Centre for Regenerative Therapies

Impact of immunoaging on regenerative processes

Gernot Längst

University of Regensburg

Targeting non-coding RNA to chromatin by triple helix formation

Jean-Ehrland Ricci

University of Nice

Deciphering the link between metabolism and anti-cancer immunosurveillance

Pascale Quignon

University of Rennes

Like master like dog: The dog as a spontaneous genetic model

Leonie Young

RCSI

Epigenetic and transcriptomic aberrations in advanced breast cancer

Patrick Harrison   

UCC

Towards therapeutic gene editing for cystic fibrosis

Lynne-Marie Postovit

Cancer Research Institute of Northern Alberta

Cellular plasticity in cancer: mechanisms of adaptation

Mani Ramaswami

TCD

Mechanisms of perpetual silencing: connecting molecules and modules to cognition

Anja Göder

University Medical Center Mainz

Class I HDACs and phosphatase PP2A influence cell fate decisions upon replication stress

Martin Lavin

University of  Queensland

ATM, role in repair of physiologically-induced DNA DSB and in protecting against lung disease

Jessica Mar

University of Queensland

One of these cells is not like the other – how variability of gene expression highlights regulatory control

Gerome Breen

King's College London

Genetic links to anxiety and depression

Paul Murray

 UL / University of Birmingham

The Epstein-Barr virus and the pathogenesis of B cell lymphoma

Geert Kops

Hubrecht Institute/ UMC Utrecht

Make no mistake: chromosomal instability and karyotype heterogeneity in cancer

Paul Stothard

University of Alberta

Finding causative mutations in livestock: new bioinformatics tools for structural variant discovery and analysis

Mikko Taipale

University of Toronto

Studying 1000 rare diseases at the same time

David Shore

University of Geneva

Replication fork barrier tolerance mechanisms in budding yeast

Tomás Ryan   

TCD

Information storage in memory engrams

Francesco Ferrari

IFOM, Milan

Chromatin 3D organization and regulation of transcription